Clinical Studies in People with Chronic Liver Disease

Posted by: I Support Research

Clinical Studies in People with Chronic Liver Disease

October is Liver Disease Awareness Month. Do you know what your liver does for your body?


Your liver is the largest internal organ in your body, and its main job is to filter blood coming from the digestive tract, before passing it to the rest of the body. The liver also detoxifies chemicals and metabolizes some medications (passes them through the bodily system). According to the American Liver Foundation, about 30 million Americans have some form of liver disease; that’s about one in 10 people in the US.


What causes liver disease?

The main causes of chronic liver disease (in which it can take months or years for the liver to fail) include:

  • Hepatitis B
  • Hepatitis C
  • Long-term alcohol consumption
  • Cirrhosis
  • Hemochromatosis (an inherited disorder that causes the body to absorb and store too much iron)
  • Malnutrition


Why are clinical studies done with people who have liver disease?

Because the liver plays such an important role in your body, and because so many people have impaired liver function, clinical trials are needed to understand how some drugs will be metabolized in a person with liver disease. These studies may require participants with mild, moderate, or severe liver disease. The studies may measure safety and tolerability of the study medication, and measure how the body processes the medication.


Why should I consider participating in a liver study with DaVita Clinical Research?

DaVita Clinical Research (DCR) works with third party researchers and other pharmaceutical and biotechnology organizations to find solutions that will help provide a better quality of life for people with liver disease through advanced medical care. Participating in a liver disease study will help researchers better understand how new or existing therapies could be used in people with liver disease.


Studies conducted by DaVita Clinical Research are conducted by a group that includes medically trained doctors and nurses. To find out more about the clinical trials for which you may be eligible, requirements to participate, and how much you get paid for participating in a clinical trial, speak to a recruiter today!


Disclaimer: Phase 1 (in-patient) clinical trials are not intended to treat a disease or condition. Phase 3 (out-patient) clinical trials may help treat an existing disease or condition. The information presented in this blog may be referring to either a phase 1 clinical trial or to a phase 3 clinical trial or to both. If you contact us regarding a trial, be sure to speak with the recruiter about whether or not the trial is intended to treat a condition.